44,913 research outputs found
Helicopter internal noise control: Three case histories
Case histories are described in which measurable improvements in the cabin noise environments of the Bell 214B, 206B, and 222 were realized. These case histories trace the noise control efforts followed in each vehicle. Among the design approaches considered, the addition of a fluid pulsation damper in a hydraulic system and the installation of elastomeric engine mounts are highlighted. It is concluded that substantial weight savings result when the major interior noise sources are controlled by design, both in altering the noise producing mechanism and interrupting the sound transmission paths
Influence of Correlated Hybridization on the Conductance of Molecular Transistors
We study the spin-1/2 single-channel Anderson impurity model with correlated
(occupancy dependent) hybridization for molecular transistors using the
numerical renormalization-group method. Correlated hybridization can induce
nonuniversal deviations in the normalized zero-bias conductance and, for some
parameters, modestly enhance the spin polarization of currents in applied
magnetic field. Correlated hybridization can also explain a gate-voltage
dependence to the Kondo scale similar to what has been observed in recent
experiments.Comment: 4 pages, 5 figure
Coordination of Purchasing and Bidding Activities Across Markets
In both consumer purchasing and industrial procurement, combinatorial interdependencies among the items to be purchased are commonplace. E-commerce compounds the problem by providing more opportunities for switching suppliers at low costs, but also potentially eases the problem by enabling automated market decision-making systems, commonly referred to as trading agents, to make purchasing decisions in an integrated manner across markets. Most of the existing research related to trading agents assumes that there exists a combinatorial market mechanism in which buyers (or sellers) can bid (or sell) service or merchant bundles. Todayâ??s prevailing e-commerce practice, however, does not support this assumption in general and thus limits the practical applicability of these approaches. We are investigating a new approach to deal with the combinatorial interdependency challenges for online markets. This approach relies on existing commercial online market institutions such as posted-price markets and various online auctions that sell single items. It uses trading agents to coordinate a buyerâ??s purchasing and bidding activities across multiple online markets simultaneously to achieve the best overall procurement effectiveness. This paper presents two sets of models related to this approach. The first set of models formalizes optimal purchasing decisions across posted-price markets with fixed transaction costs. Flat shipping costs, a common e-tailing practice, are captured in these models. We observe that making optimal purchasing decisions in this context is NP-hard in the strong sense and suggest several efficient computational methods based on discrete location theory. The second set of models is concerned with the coordination of bidding activities across multiple online auctions. We study the underlying coordination problem for a collection of first or second-price sealed-bid auctions and derive the optimal coordination and bidding policies.
New method for critical failure prediction of complex systems
Rigorous analytical technique, called criticality determination methodology /or CD technique/ determines the probability that a given complex system will successfully achieve stated objectives. The CD technique identifies critical elements of the system by a failure mode and effects analysis
Cell surface localization of tissue transglutaminase is dependent on a fibronectin-binding site in its N-terminal beta-sandwich domain
Increasing evidence indicates that tissue transglutaminase (tTG) plays a role in the assembly and remodeling of extracellular matrices and promotes cell adhesion. Using an inducible system we have previously shown that tTG associates with the extracellular matrix deposited by stably transfected 3T3 fibroblasts overexpressing the enzyme. We now show by confocal microscopy that tTG colocalizes with pericellular fibronectin in these cells, and by immunogold electron microscopy that the two proteins are found in clusters at the cell surface. Expression vectors encoding the full-length tTG or a N-terminal truncated tTG lacking the proposed fibronectin-binding site (fused to the bacterial reporter enzyme β-galactosidase) were generated to characterize the role of fibronectin in sequestration of tTG in the pericellular matrix. Enzyme-linked immunosorbent assay style procedures using extracts of transiently transfected COS-7 cells and immobilized fibronectin showed that the truncation abolished fibronectin binding. Similarly, the association of tTG with the pericellular matrix of cells in suspension or with the extracellular matrix deposited by cell monolayers was prevented by the truncation. These results demonstrate that tTG binds to the pericellular fibronectin coat of cells via its N-terminal β-sandwich domain and that this interaction is crucial for cell surface association of tTG
The bosonic Kondo effect
The Kondo effect is associated with the formation of a many-body ground state
that contains a quantum-mechanical entanglement between a (localized) fermion
and the free fermions. We show that a bosonic version of the Kondo effect can
occur in degenerate atomic Fermi gases near the Feshbach resonance. We also
discuss how this bosonic Kondo effect can be observed experimentally.Comment: 4 pages, 2 figures, some references added, some removed. More
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